Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT07138872

Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy

Led by Gaziosmanpasa Research and Education Hospital · Updated on 2025-08-24

84

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones. Surgical position may influence intraoperative and postoperative hemodynamic stability. Prone positioning can increase intrathoracic pressure and reduce venous return, whereas supine positioning may provide greater hemodynamic stability. A total of 84 patients will be randomized to undergo PNL in prone or supine positions. Primary outcomes include changes in hemodynamic parameters during surgery. Results may guide surgical position selection, especially in patients with potential hemodynamic risk.

CONDITIONS

Official Title

Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • ASA physical status I-III
  • Presence of renal calculi indicated for PNL
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Uncontrolled coagulopathy
  • Previous renal surgery
  • Severe cardiac, pulmonary, or neurological disease
  • Preoperative urinary tract infection (non-sterile urine culture)
  • Surgery duration <60 minutes or >120 minutes
  • Preoperative blood transfusion
  • Multiple access tracts

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Gaziosmanpaşa Training and Research Hospital

Istanbul, Turkey (Türkiye), 34275

Actively Recruiting

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Research Team

A

ARİF BURAK KEÇEBAŞ, UROLOGY CLINIC DOCTOR

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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