Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06910891

Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients

Led by University Hospital, Limoges · Updated on 2025-11-21

556

Participants Needed

6

Research Sites

79 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Despite early treatment, the deterioration and mortality of sepsis patients remains high. A possible explanation could be persistent tissue hypoperfusion, or undetected in the early phase despite the normalization of macro-hemodynamic parameters. This interventional study evaluates the impact of measuring microcirculation parameters by nurses on patient prognosis through early initiation of vascular filling.

CONDITIONS

Official Title

Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Admitted to the Emergency Department for suspected sepsis for less than 6 hours based on Sepsis-3 definitions
  • High likelihood of infection with fever ≥ 38.3°C and NEWS 2 score ≥ 2
  • Affiliated with a social security system
  • Agreed to participate in the study
Not Eligible

You will not qualify if you...

  • Arterial blood pressure ≤ 100 mmHg on admission
  • Already received a 500 mL fluid filling test over 30 minutes
  • Considered moribund by the investigator
  • Pregnant or breastfeeding
  • Under legal guardianship, curatorship, or judicial protection

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 6 locations

1

Brive Hospital

Brivé, France, 19100

Actively Recruiting

2

Guéret Hospital

Guéret, France, 23000

Actively Recruiting

3

Limoges University Hospital

Limoges, France, 87000

Actively Recruiting

4

Saint Junien Hospital

Saint-Junien, France, 87200

Actively Recruiting

5

Tulle Hospital

Tulle, France, 19012

Actively Recruiting

6

Ussel Hospital

Ussel, France, 19200

Actively Recruiting

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Research Team

A

Anaelle NARDOT-SUCHAUD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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