Actively Recruiting
Hemodynamic Management Following Acute Traumatic Spinal Cord Injury
Led by The University of Texas Health Science Center, Houston · Updated on 2024-12-11
228
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center, Houston
Lead Sponsor
T
Trauma Research and Combat Casualty Care Collaborative (TRC4)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to assess the effect of various hemodynamic management strategies on functional neurologic outcomes and non-neurologic adverse events in the first 5 days following acute spinal cord injury (SCI). The hemodynamic management strategies assessed include targeting a mean arterial blood pressure (MAP) goal of 85-90 mmHg, targeting a spinal cord perfusion pressure (SCPP) goal of ≥65 mmHg, or targeting normal hemodynamics, which is a MAP goal of ≥65 mmHg.
CONDITIONS
Official Title
Hemodynamic Management Following Acute Traumatic Spinal Cord Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Traumatic spinal cord injury
You will not qualify if you...
- Injury from trauma that penetrates the spinal cord, such as gunshot or knife wound causing cord transection
- Preexisting neurologic or spinal cord injury
- Severe traumatic brain injury with Glasgow Coma Scale score below 8 at 24 hours after injury
- Traumatic injuries preventing spine surgery within 24 hours of presentation
- Injury or illness requiring specialized blood pressure management (e.g., aortic injury, aortic dissection, hemorrhagic stroke)
- History of neuromotor disorders like cerebral palsy or Parkinson disease
- Not expected to survive more than 24 hours
- Cord transection confirmed by radiologist and spine surgery team
- Injury below spinal cord level L1
- Prisoners
- Pregnant women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
D
David Meyer, MD, MS, FACS
CONTACT
E
Erin Fox
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here