Actively Recruiting

Age: 18Years +
All Genders
NCT06448949

Hemodynamic Study of In-Stent Stenosis(I) After Flow Diverter(F) Based on 3D-DSA(D) Combined With TCCD(T)

Led by Zhujiang Hospital · Updated on 2025-07-18

200

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

DTFI is a single-center, prospective cohort study aimed at evaluating the hemodynamics of in-stent stenosis after flow diverter implantation, seeking to identify the threshold effect of blood flow in stenosis.

CONDITIONS

Official Title

Hemodynamic Study of In-Stent Stenosis(I) After Flow Diverter(F) Based on 3D-DSA(D) Combined With TCCD(T)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older, male or non-pregnant female
  • Diagnosis of intracranial aneurysm confirmed by digital subtraction angiography (DSA)
  • Intracranial aneurysms treated with flow diverter (FD)
  • DSA follow-up of at least 1 month
Not Eligible

You will not qualify if you...

  • Traumatic, infectious aneurysms, or aneurysms associated with arteriovenous malformations (AVM) or vasculitis
  • Previously treated recurrent or target aneurysm with craniotomy clipping or other endovascular interventions
  • Aneurysms located where transcranial color-coded Doppler (TCCD) cannot detect flow
  • Known familial clustering history or expected survival less than 1 year
  • Preoperative clinical assessment with Modified Rankin Scale (mRS) score 3 or higher
  • Known allergy or contraindication to antiplatelet drugs, anticoagulants, contrast agents, anesthetics, or metal alloys used in devices
  • Severe respiratory, liver, or kidney disease (e.g., creatinine 3.0 mg/dL or higher, excluding dialysis) or coagulation disorders
  • Major surgery within 30 days before or planned within 60 days after consent
  • Pregnant or lactating women or positive pregnancy test

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

DuanChuanzhi

Guangzhou, Guangdong, China, 528400

Actively Recruiting

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Research Team

Z

Zhang Xin, MD

CONTACT

J

Jia Zhi kun, MMed

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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