Actively Recruiting

Phase 4
Age: 19Years - 40Years
FEMALE
NCT07322419

Hemodynamics During Cesarean Delivery Under Spinal Anesthesia With Norepinephrine Versus Ephedrine

Led by Mansoura University · Updated on 2026-01-14

200

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Echocardiography will be used to measure cardiac output and calculate other important hemodynamic variables in healthy patients with full-term singleton pregnancy during cesarean delivery under conventional spinal anesthesia using 2 different vasopressor drugs: norepinephrine in 1 group versus ephedrine in another group.

CONDITIONS

Official Title

Hemodynamics During Cesarean Delivery Under Spinal Anesthesia With Norepinephrine Versus Ephedrine

Who Can Participate

Age: 19Years - 40Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • American Society of Anesthesiologists physical status II.
  • Singleton, full term pregnancy.
  • Scheduled cesarean delivery under spinal anesthesia.
Not Eligible

You will not qualify if you...

  • Height <150 or >180 cm.
  • Weight <60 or >110 kg.
  • Body mass index (BMI) <18.5 or ≥35 kg/m².
  • Women presenting in labor.
  • Any contraindication to spinal anesthesia: increased intracranial pressure, coagulopathy, or local skin infection.
  • Chronic or pregnancy-induced hypertension.
  • Baseline systolic blood pressure >140 mm Hg.
  • Hemoglobin <10 g/dl.
  • Diabetes mellitus, cardiovascular, cerebrovascular, or renal disease.
  • Polyhydramnios or known significant fetal abnormalities.
  • Current administration of vasoactive drugs such as: beta blockers, salbutamol, or thyroxin.

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Trial Site Locations

Total: 1 location

1

Department of Anesthesia and Surgical Critical Care, Mansoura University Hospitals

Al Mansurah, Dakahlia Governorate, Egypt, 35511

Actively Recruiting

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Research Team

M

Mohamed M Tawfik, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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