Actively Recruiting
Hemoglobin Levels for Blood Transfusions During and After Surgery
Led by Ottawa Hospital Research Institute · Updated on 2025-07-31
384
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this pilot clinical trial is to learn if it is achievable to conduct a large-scale clinical trial whereby, the investigators will compare two ways of deciding when to give a blood transfusion during surgery. Participants in this study are adults undergoing surgery with a risk of significant blood loss. The main question it aims to answer is: * Is a trial designed to definitively test and compare two different red blood cell transfusion strategies feasible? Participants will: * Receive blood transfusions during surgery based on a higher (less than 90 g/L) or a lower (less than 70 g/L) hemoglobin value. * Complete questionnaires at 30 and 90 days after surgery.
CONDITIONS
Official Title
Hemoglobin Levels for Blood Transfusions During and After Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 18 years or older
- Scheduled for elective or urgent surgery
- Expected risk of red blood cell transfusion of at least 10 percent
- Preoperative hemoglobin level less than 130 g/L
- Hemoglobin level of 100 g/L or less at any time during surgery
You will not qualify if you...
- Active major bleeding as the reason for surgery (e.g., ruptured aneurysm, multiple severe injuries)
- Heart attack or acute coronary syndrome within the past 6 weeks
- Undergoing cardiac surgery
- Undergoing liver transplantation
- Surgery for moderate to severe traumatic brain injury (Glasgow Coma Scale score 12 or less)
- Pregnant or undergoing obstetrical surgery
- Refusal to receive blood products
- Unable to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Ottawa Hospital
Ottawa, Ontario, Canada, K1H 8L6
Actively Recruiting
Research Team
Z
Zanna Vanterpool, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here