Comparing Heparin Solution and Anti-adhesion Barrier Gel to Prevent Intrauterine Adhesions After Operative Hysteroscopy in Women Aged 25 to 50

What This Trial Is About

This research aims to compare the effects of intrauterine heparin solution versus anti-adhesion hyaluronic acid barrier gel in preventing intrauterine adhesions following operative hysteroscopy. The study focuses on women undergoing this procedure for conditions such as infertility, irregular bleeding, or uterine abnormalities. The goal is to understand how these treatments impact post-surgical complications and fertility outcomes. Participants will receive one of two treatments immediately after operative hysteroscopy either 3 ml of heparin solution containing 5000 IU heparin or 2 ml of a biodegradable anti-adhesion barrier gel. Both treatments are applied directly into the uterine cavity. The study uses a randomized design with single masking to compare these interventions. Women will be followed up with a diagnostic hysteroscopy 4 to 8 weeks after surgery to assess the presence and severity of intrauterine adhesions and determine if further surgical treatment is needed. Data on menstrual patterns and pregnancy success will be collected for up to 12 months. Researchers will monitor outcomes such as adhesion formation, irregular bleeding, and fertility improvement during this period.

Heparin Solution Versus Anti-adhesion Barrier Gel for Intrauterine Adhesions Prevention After Operative Hysteroscopy