Actively Recruiting

Phase Not Applicable
Age: 18Years - 100Years
All Genders
NCT05209841

Heparinization vs Salinization of the Peripheral Venous Catheter

Led by Consorci Sanitari de l'Alt Penedès i Garraf · Updated on 2025-06-25

3450

Participants Needed

1

Research Sites

225 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Randomized, double-blind clinical trial to compare the efficacy of catheter sealing with saline, compared to low-dose heparin. 3,450 patients hospitalized at the Hospital Residencia Sant Camil, in Catalonia (Spain), will be randomized to each branch of study. The primary outcome will be the percentage of catheters removed due to obstruction in each branch of study. As secondary outcomes, the number of catheter-associated phlebitis, catheter-associated bacetrihemia, extravasation, and catheter loss will be measured. For the primary outcome, a superiority analysis will be carried out in terms of the percentage of obstructed catheters in each branch of the study.

CONDITIONS

Official Title

Heparinization vs Salinization of the Peripheral Venous Catheter

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients older than 18 years, admitted to the Hospital Residencia Sant Camil
  • Patients with at least one peripheral venous line for discontinuous treatment, not placed in a medical emergency
  • Written informed consent
Not Eligible

You will not qualify if you...

  • Allergy to heparin
  • Patients treated with unfractionated sodium heparin
  • Patients on dialysis
  • Patients with venous catheters for diagnostic tests
  • Patients with venous catheters for blood transfusion
  • Severe heparin-induced thrombocytopenia in recent months
  • Active uncontrollable bleeding during admission
  • Brain aneurysm or dissecting aorta except with corrective surgery
  • Confirmed or suspected cerebrovascular hemorrhage
  • Severe uncontrolled hypertension
  • Severe platelet coagulation abnormalities (platelets <30,000, TP >1.7, APTT ratio >1.7)
  • Participation in another clinical trial affecting venous catheter patency

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Hospital Residència Sant Camil

Sant Pere de Ribes, Barcelona, Spain, 08810

Actively Recruiting

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Research Team

E

Esther Moreno Rubio

CONTACT

N

Noemí Casaponsa

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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