Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05205954

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease

Led by Massachusetts General Hospital · Updated on 2025-07-24

30

Participants Needed

2

Research Sites

75 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research study is evaluating a program that entails a healthcare at home intervention for people with advanced liver disease.

CONDITIONS

Official Title

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients 18 years or older with cirrhosis diagnosed by histology, radiology, or elastography
  • Presenting to the emergency department or inpatient general medicine service
  • Have at least one of the following: ascites requiring diuretics or serial large volume paracenteses, hepatic hydrothorax requiring diuretics, or hepatic encephalopathy requiring medications
Not Eligible

You will not qualify if you...

  • History of solid organ transplantation
  • Currently on hemodialysis
  • MELD score greater than 20
  • Score less than 10 on Simplified Animal Naming Test (S-ANT1)
  • Current admission for hemodynamically significant gastrointestinal bleeding or alcohol withdrawal
  • Require routine administration of controlled substances
  • Deemed ineligible by MGH Home Hospital, inpatient medicine, or hepatology clinician evaluation
  • Meet any existing Mass General Brigham home hospital exclusion criteria

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

2

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

N

Nneka Ufere, MD, MSCE

CONTACT

W

William Munroe, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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