Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06548529

HER2 Expression of HER2 Affibody-based PET/CT to Predict Response in Bladder Cancer Patients Treated With ADC

Led by Peking University Cancer Hospital & Institute · Updated on 2024-08-23

30

Participants Needed

1

Research Sites

234 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To use the molecular PET radionuclide (F-18) labelled HER2 Affibody to evaluate the predictive and prognostic value of HER2 expression in bladder cancer patients treated with HER2 ADC

CONDITIONS

Official Title

HER2 Expression of HER2 Affibody-based PET/CT to Predict Response in Bladder Cancer Patients Treated With ADC

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 80 years old with ECOG performance status 0 or 1
  • Unresectable or metastatic bladder cancer
  • HER2 positive or suspicious positive tumors
  • Previously treated with trastuzumab and taxane in advanced setting or progressed within 6 months after neoadjuvant or adjuvant trastuzumab and taxane treatment
  • Adequate cardiac, bone marrow, kidney, liver, and blood clotting function
  • Currently receiving anti-HER2 ADC treatment
  • Life expectancy greater than 3 months
Not Eligible

You will not qualify if you...

  • Significant liver or kidney dysfunction
  • Pregnant or planning to become pregnant
  • Unable to remain still for half an hour
  • Refusal to participate in the clinical research
  • Claustrophobia or other mental disorders
  • Any other condition deemed unsuitable by researchers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

uEXPLORER total-body PET/CT scanner (United Imaging, China)

Beijing, China

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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