Actively Recruiting

Phase Not Applicable
All Genders
Healthy Volunteers
NCT02747888

Hereditary Risk Factors for Thyroid Cancer

Led by Dana-Farber Cancer Institute · Updated on 2025-05-19

250

Participants Needed

1

Research Sites

678 weeks

Total Duration

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AI-Summary

What this Trial Is About

Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules. * In this study, family and medical history information is collected alongside a blood or saliva sample for genetic studies. * Individuals with a past or present childhood thyroid cancer/nodule or a thyroid cancer suspected to be inherited in their family are invited to participate.

CONDITIONS

Official Title

Hereditary Risk Factors for Thyroid Cancer

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Individual pediatric patient with current or previous known or suspected thyroid cancer or nodule(s).
  • Individual adult patient with current or previous known or suspected thyroid cancer or nodule(s) if they come from a family with a high suspicion of hereditary cancer.
  • Individuals from families with a high suspicion of hereditary thyroid cancer including:
  • Families with a current or previous diagnosis of thyroid cancer or nodule occurring in childhood (under 18 years old).
  • Families with thyroid cancer in multiple individuals.
  • Families with thyroid cancer and a known genetic syndrome.
  • Families with thyroid cancer and a suspected genetic syndrome such as multiple childhood cancers, multiple primary cancers, or multiple endocrinopathies in the family.
Not Eligible

You will not qualify if you...

  • Individuals who are unable to give informed consent.
  • Individuals who are unable to complete study materials.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

J

Junne Kamihara, MD, PhD

CONTACT

S

Sarah Hunt, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

2

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