Actively Recruiting
Hetrombopag in Promoting Platelet Engraftment After Auto-HSCT in Children With Neuroblastoma
Led by Beijing Children's Hospital · Updated on 2025-12-03
30
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if hetrombopag promotes platelet engraftment in neuroblastoma children undergoing autologous hematopoietic stem cell transplantation. The main question it aims to answer is: · Does drug hetrombopag promote platelet engraftment? Participants will take hetrombopag every day for 6 weeks or until platelet \> 100\*10\^9/L.
CONDITIONS
Official Title
Hetrombopag in Promoting Platelet Engraftment After Auto-HSCT in Children With Neuroblastoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Younger than 18 years old
- Diagnosed with neuroblastoma
- ECOG performance status of 2 or less
- Receiving first autologous hematopoietic stem cell transplantation
- Participant or legal guardian agrees to participate and signs informed consent
You will not qualify if you...
- Liver enzymes ALT or AST greater than 3 times the normal upper limit, or total bilirubin greater than 1.5 times the normal upper limit
- History of congestive heart failure, arrhythmia, or peripheral blood clots requiring medication in the past year
- History of heart attack or stroke within the past 3 months
- Having thromboembolic diseases
- Any other conditions deemed unsuitable by the researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Stem Cell Transplantation, Beijing Children's Hospital, Capital Medical University
Beijing, China
Actively Recruiting
Research Team
D
Dr. Yang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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