Actively Recruiting
A Randomized Controlled Trial Using a Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer
Led by Virginia Commonwealth University · Updated on 2026-05-22
126
Participants Needed
5
Research Sites
N/A
Total Duration
On this page
Sponsors
V
Virginia Commonwealth University
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of the Computerized Symptom Assessment Tool (C-SCAT) compared to usual care on improving self-efficacy for managing symptoms and symptom self-management behaviors in adolescents and young adults with cancer. This randomized controlled trial involves participants who are within the first three months of a cancer diagnosis and receiving cancer treatment defined as prescribed infusions like chemotherapy or immunotherapy. Participants will be randomly assigned to one of two groups. One group will use the C-SCAT tool during three clinic visits over about 12 weeks, where they assess and describe their symptoms in detail before meeting with their healthcare providers. The other group will receive usual symptom care during their scheduled visits for up to 12 weeks, with study staff maintaining contact to encourage ongoing participation. During the study, participants will complete symptom assessments and questionnaires at baseline, immediately after the intervention, and at follow-up to measure self-efficacy for symptom management and symptom self-management behaviors. Researchers will also evaluate symptom severity, distress, and social function using various scales. The total participation period includes the intervention and follow-up assessments, with outcomes measured at specific timepoints to understand the impact of the C-SCAT tool.
CONDITIONS
Brief Title
Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Has received at least 1 cycle of cancer treatment and is within 3 months of receiving that first cycle of treatment
- Receiving regularly scheduled cancer treatment and will be receiving at least three more cycles
- Reports at least 1 symptom related to cancer and/or its treatment
- Able to speak, read, and write English as required for completion of the C-SCAT and study measures
You will not qualify if you...
- Cognitive and/or physical inability to complete study measures
AI-Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to about 12 weeks, depending on cancer treatment schedule
Participants receive cancer treatment with infusion (e.g., chemotherapy, immunotherapy). Those in the intervention group complete the Computerized Symptom Assessment Tool (C-SCAT) prior to three clinic visits to improve symptom self-management. Those in the control group receive usual care with three contacts from study staff during the intervention period.
3 clinic visits for cancer treatment
Duration - 4 weeks following treatment
Participants are assessed for symptom self-management and social function outcomes up to 4 weeks after the treatment period ends.
1 follow-up visit
Trial Site Locations
Total: 5 locations
1
Children's Mercy Hospital
Kansas City, Missouri, United States, 64108
Actively Recruiting
2
University of Utah Huntsman Cancer Institute (HCI)
Salt Lake City, Utah, United States, 84112
Actively Recruiting
3
University of Utah Primary Children's Hospital
Salt Lake City, Utah, United States, 84113
Actively Recruiting
4
Virginia Commonwealth University
Richmond, Virginia, United States, 23298
Actively Recruiting
5
Seattle Children's Hospital @ University of Washington
Seattle, Washington, United States, 98105
Active, Not Recruiting
Research Team
G
Grace Hodges
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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