Actively Recruiting

Age: 18Years +
All Genders
NCT04060706

Heuristics, Algorithms and Machine Learning: Evaluation & Testing in Radiation Therapy

Led by CCTU- Cancer Theme · Updated on 2021-08-02

310

Participants Needed

1

Research Sites

433 weeks

Total Duration

On this page

Sponsors

C

CCTU- Cancer Theme

Lead Sponsor

U

University of Cambridge

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Hamlet.rt study is a prospective data collection and patient questionnaire study for patients undergoing image-guided radiotherapy with curative intent. The aim of the study is to use novel machine learning and mathematical techniques to build a model that can predict the risk of significant side effects from radiotherapy treatment for an individual patient: using calculations of normal tissue dose from radiotherapy treatment planning and patient baseline characteristics derived from image and non-image data, continuously updated as the patient is reviewed both during and after treatment. A secondary goal of the project is to facilitate research in machine learning and medical image processing for radiation therapy through the creation of a discoverable and shared data resource for research use.

CONDITIONS

Official Title

Heuristics, Algorithms and Machine Learning: Evaluation & Testing in Radiation Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing and able to give informed consent for participation in the study
  • Male or female
  • Aged 18 years or older
  • Diagnosed with primary prostate cancer, head and neck cancer, lung cancer, or brain tumour
  • Treated with curative intent
  • Suitable for radical image guided radiotherapy
  • WHO ECOG performance status 0 or 1
  • Expected survival of 18 months or more
Not Eligible

You will not qualify if you...

  • Not willing or able to complete study requirements, including accessing and completing web-based long-term follow-up questionnaires

AI-Screening

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Trial Site Locations

Total: 1 location

1

Cambridge University Hospitals NHS Foundation Trust

Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ

Actively Recruiting

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Research Team

M

Meena Murthy

CONTACT

C

CCTU Cancer

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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