Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06470516

The Hi-tACS on Cognitive Function in Patients With Schizophrenia

Led by Sir Run Run Shaw Hospital · Updated on 2026-03-02

100

Participants Needed

2

Research Sites

104 weeks

Total Duration

On this page

Sponsors

S

Sir Run Run Shaw Hospital

Lead Sponsor

Q

Quzhou Third hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with schizophrenia.

CONDITIONS

Official Title

The Hi-tACS on Cognitive Function in Patients With Schizophrenia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Meets the diagnostic criteria for schizophrenia according to DSM-5.
  • Age 18 years old.
  • Right-handed.
  • Willing to participate and sign an informed consent form, or have a legal guardian sign if unable.
  • Clinically stable and on a stable dose of antipsychotic medication for at least 4 weeks.
  • Montreal Cognitive Assessment score 10 points.
Not Eligible

You will not qualify if you...

  • Psychotic disorders caused by split affective disorder, bipolar disorder, intellectual disability, anxiety spectrum disorders, drugs, alcohol, or other psychoactive substances.
  • Severe or unstable organic diseases, history of brain tumors or epilepsy.
  • Received MECT or TMS treatment within 1 month before enrollment.
  • Compromised skin integrity at electrode placement sites or allergy to electrode gel or adhesive.
  • Implants of metal or electronic devices such as pacemakers, cochlear implants, deep brain stimulators, aneurysm clips, or internal fixation devices.
  • Participation in any other clinical trials within 1 month prior to baseline.
  • Pregnant or breastfeeding women.
  • Investigator believes participation is inappropriate.

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Sir Run Run Shaw Hospital

Hanzhou, Zhejiang, China, 310020

Actively Recruiting

2

Quzhou Third Hospital

Quzhou, Zhejiang, China, 324003

Actively Recruiting

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Research Team

J

Jinsong Tang, Doctorate

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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