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HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase Not Applicable
Age: 75Years +
All Genders
Healthy Volunteers
ID04987814

High-Definition Surface Electromyography to Diagnose Sarcopenia in Older Adults A Study of Muscle Function and Mass in People 75 Years and Older

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-05-23

175

Participants Needed

6

Research Sites

4 weeks

Total Duration

AI-Summary

What this Trial Is About

Sarcopenia is a progressive muscle disorder marked by the loss of muscle mass and function, leading to increased risks like falls, frailty, and death. This study aims to explore a new, non-invasive diagnostic method using high-definition surface electromyography HD-sEMG technology to better identify sarcopenia in older adults. The research is a monocentric, descriptive, cross-sectional pilot project including people aged 75 and older who are hospitalized and suspected of sarcopenia based on a screening questionnaire score. Participants will undergo the HD-sEMG procedure, which records muscle activation signals from the rectus femoris muscle during knee extension, either lying down or sitting, depending on their ability. Additional assessments include muscle ultrasounds using a handheld device, physical activity questionnaires, and body composition analysis via DEXA scans. Muscle strength will be measured through handgrip tests, and physical performance will be evaluated using established scoring methods. During the study, participants will have various assessments including muscle mass, fat thickness, and electromyographic signals collected within the first week after inclusion, with follow-up HD-sEMG muscle data collected one month later. Researchers will also track falls, mortality rates, and other health indicators through medical records. The total duration for each participant is 37 months, including 36 months for inclusion and a one-month follow-up as part of routine care.

CONDITIONS

Brief Title

High-definition Surface Electromyography Markers for the Diagnosis of Sarcopenia

Research Team

K

Kiyoka KINUGAWA, MD PhD

S

Sofiane BOUDAOUD, Pr

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