Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT05738174

High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction

Led by Berthold Langguth, MD, Ph.D. · Updated on 2025-09-19

72

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a two-arm randomized placebo-controlled trial in which 72 patients with alcohol addiction are treated with high-dose accelerated intermittent theta burst stimulation (TBS).

CONDITIONS

Official Title

High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Alcohol dependence according to ICD-10 (F10.2)
  • Desire to reduce or abstain from alcohol drinking
  • Male or female
  • Age between 18 and 65 years
  • Residency in Germany and German speaking
  • Written informed consent
Not Eligible

You will not qualify if you...

  • Contraindications for transcranial magnetic stimulation such as electric devices or metal parts in the body (e.g., pacemaker)
  • Relevant neurological or internal diseases as judged by the study investigator
  • Previous treatment with transcranial magnetic stimulation
  • Participation in other clinical trials during treatment
  • Pregnancy or breastfeeding
  • Positive breath test for alcohol
  • Legal care or placement in a psychiatric hospital
  • Use of disulfiram, acamprosate, topiramate, baclofen, naltrexone, or nalmefene
  • Acute psychiatric conditions requiring inpatient treatment or medication changes within the last month
  • Severe chronic psychiatric illnesses such as schizophrenia, schizoaffective disorder, or bipolar disorder
  • Inability to complete study or follow-up questionnaires as judged by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Psychiatry and Psychotherapy, University of Regensburg

Regensburg, Germany, 93055

Actively Recruiting

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Research Team

M

Martin Schecklmann, Prof.

CONTACT

J

Johannes Huebner

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction | DecenTrialz