Actively Recruiting
High-dose Dual Therapy and Minocycline-cotaining Quadruple Therapy for Helicobacter Pylori Infection
Led by Shanghai Jiao Tong University School of Medicine · Updated on 2024-12-30
200
Participants Needed
10
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a multicentra, prospective study. The enrolled patients are HP positive. They are diagnosed as HP positive by rapid urease test and/or 13C urea breath test. According to the declaration of Helsinki, 200 patients will be included in this study. After obtaining the written informed consent of the patients, HP culture and drug sensitivity test will be conducted on all the selected patients with the success rate, adverse reactions, compliance, antibiotic resistance of HP and its impact on HP eradication.
CONDITIONS
Official Title
High-dose Dual Therapy and Minocycline-cotaining Quadruple Therapy for Helicobacter Pylori Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability and willingness to participate in the study and to sign and give informed consent
- Confirmed Helicobacter pylori infection
- Age between 18 and 70 years
You will not qualify if you...
- Pregnant and lactating women
- History of gastrointestinal cancers
- Previous subtotal gastrectomy
- Serious dysfunction of heart, liver, kidney, lung, or other important organs or congenital diseases such as grade IV cardiac insufficiency, liver failure, uremia, respiratory failure, hemophilia, Wilson disease
- History of blood diseases
- Allergy to study drugs
- Refusal by patient or guardian to participate
- Alcohol or drug abuse or poor treatment compliance
- No legal capacity or poor self-knowledge
- Use of antibiotics, bismuth, antisecretory drugs, or Chinese herbal medicine within 8 weeks before the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
Hebi People's Hospital
Hebi, Henan, China
Actively Recruiting
2
Jiaozuo People's Hospital
Jiaozuo, Henan, China
Actively Recruiting
3
Luoyang central Hospital
Luoyang, Henan, China
Actively Recruiting
4
The first people's hospital of ping ding shan
Pingdingshan, Henan, China
Actively Recruiting
5
Xuchang central Hospital
Xuchang, Henan, China
Actively Recruiting
6
The Second Affiliated Hospital of Henan University of science and technology
Zhengzhou, Henan, China
Actively Recruiting
7
The Third People's Hospital of Zhengzhou
Zhengzhou, Henan, China
Actively Recruiting
8
Zhengzhou People's Hospital
Zhengzhou, Henan, China
Actively Recruiting
9
Zhoukou Central Hospital
Zhoukou, Henan, China
Actively Recruiting
10
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, Shanghai Municipality, China, 200127
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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