Actively Recruiting
The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial (Cardiac Output Study)
Led by Philips Clinical & Medical Affairs Global · Updated on 2026-02-27
75
Participants Needed
2
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to compare cardiac output (CO), fluid responsiveness, and related measurements between the Philips AMC and PAC (Swan-Ganz) in ICU or surgical patients.
CONDITIONS
Official Title
The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial (Cardiac Output Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years and older
- Indication for PAC (Swan-Ganz)
- Indication for radial arterial line
- Ability to understand and speak the local language or Spanish (for US sites) to provide voluntary written informed consent prior to study procedures
You will not qualify if you...
- Emergency surgery
- ICU or surgical positioning where both arms are tucked
- Inability to place the Philips AMC appropriately due to subject anatomy or condition
- Known pregnancy or lactating women (self-report)
- Patients treated with an intra-aortic balloon pump
- Measurements taken in the lateral position
- Currently participating in an investigational drug or another device study that clinically interferes with the study endpoints
- Upper arm circumference < 19 cm or > 43 cm
- BMI > 45
- At the PI's discretion, subject does not qualify to participate in the study for any reasons that are not mentioned above
AI-Screening
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Trial Site Locations
Total: 2 locations
1
UVA Health
Charlottesville, Virginia, United States, 22904
Actively Recruiting
2
Universitätsklinikum Hamburg Eppendorf
Hamburg, Free and Hanseatic City of Hamburg, Germany, 20246
Actively Recruiting
Research Team
L
Lea Egger
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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