Using High-Flow Nasal Cannula to Prevent Low Oxygen Levels During Sedated Gastrointestinal Endoscopy in Patients at High Risk of Obstructive Sleep Apnea

What this Trial Is About

Researchers are investigating whether the High-Flow Nasal Cannula HFNC can reduce the risk of hypoxia during sedated gastrointestinal endoscopy in patients at high risk for obstructive sleep apnea OSA. These patients are identified using the STOP-BANG questionnaire, with a score of 5 or higher indicating increased susceptibility to hypoxia during sedation. Although initial studies suggest HFNC might help, more evidence is needed for patients with high-risk OSA. Participants are randomly assigned to one of two groups one group uses the High-Flow Nasal Cannula for oxygen delivery, while the other uses a regular nasal cannula. The study focuses on sedated gastrointestinal procedures such as gastroscopy, colonoscopy, or both combined, with an expected procedure time of up to 45 minutes. This multicenter trial is designed to compare these two oxygenation methods during the procedure. During the hospital stay, lasting about 2 hours on average, researchers will monitor participants for the occurrence of hypoxia, sub-clinical respiratory depression, and severe hypoxia. The study tracks these outcomes closely to understand the safety and effectiveness of HFNC in this setting. Participants will be carefully observed throughout the procedure and recovery to provide detailed information on respiratory status under sedation.

High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients