Actively Recruiting
High - Flow Nasal Cannula Versus Conventional Nasal Cannula During Endobronchial Ultrasound Procedure
Led by The University Clinic of Pulmonary and Allergic Diseases Golnik · Updated on 2024-10-15
150
Participants Needed
4
Research Sites
35 weeks
Total Duration
On this page
Sponsors
T
The University Clinic of Pulmonary and Allergic Diseases Golnik
Lead Sponsor
N
National and Kapodistrian University of Athens
Collaborating Sponsor
AI-Summary
What this Trial Is About
EBUS bronchoscopy is performed in most centers under local anesthesia and moderate sedation. Both the bronchoscopy itself and the sedation can lead to decreased ventilation and a drop in oxygen saturation in the body. Typically, oxygen is administered during the procedure via a nasal cannula at a flow rate of 6l/min. The aim of the study is to compare a new method - a nasal cannula with high flow - to the standard cannula. The primary objective is to demonstrate that the new method is more effective at preventing desaturation during the procedure. Patients will be randomized into two groups before bronchoscopy and monitored. The bronchoscopy will be performed in the same way for both groups. The only difference between the groups will be in the method of oxygen administration during EBUS bronchoscopy.
CONDITIONS
Official Title
High - Flow Nasal Cannula Versus Conventional Nasal Cannula During Endobronchial Ultrasound Procedure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients older than 18 years
- ASA physical status classification I to III
- Normal pre-procedural oxygen level (pO2 > 8.0 kPa) without oxygen supplementation
- Normal pre-procedural carbon dioxide level (pCO2 < 6.7 kPa) without oxygen supplementation
You will not qualify if you...
- Patient refuses to participate in the study
- Contraindication for topical anesthesia, intravenous sedation, or bronchoscopy
- Pregnancy
- Contraindication for high-flow nasal cannula including nasopharyngeal obstruction or blockage
- Unable to tolerate high-flow nasal cannula at 60 liters per minute (tested before procedure)
- Procedure duration shorter than 10 minutes
- Fewer than 3 EBUS-TBNA procedures performed
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
University Hospital Centre Zagreb - Jordanovac
Zagreb, City of Zagreb, Croatia, 1000
Actively Recruiting
2
National and Kapodistrian University of Athens
Athens, Athens, Greece, 106 79
Actively Recruiting
3
Clinica Universitaria de Pneumologia, Hospital de Santa Maria
Lisbon, Lisbon District, Portugal, 1649-028
Actively Recruiting
4
University Clinic Golnik
Golnik, Golnik, Slovenia, 4204
Actively Recruiting
Research Team
A
Ales Rozman, MD, PhD
CONTACT
S
Sonja Badovinac, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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