Actively Recruiting

Phase Not Applicable
Age: 0Months - 12Months
All Genders
NCT06321133

High Flow Nasal Cannula Weaning in Acute Bronchiolitis

Led by Kuopio University Hospital · Updated on 2025-09-03

50

Participants Needed

4

Research Sites

254 weeks

Total Duration

On this page

Sponsors

K

Kuopio University Hospital

Lead Sponsor

C

Central Finland Hospital District

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical study is to compared two different strategies to end high flow nasal cannula treatment in acute bronchiolitis. This study compared the immediate ending of high flow treatment to weaning strategy, in which the flow rate is gradually decreased. The aim is to assess if the immediate ending shortens the hospitalization time and whether it is a safe strategy.

CONDITIONS

Official Title

High Flow Nasal Cannula Weaning in Acute Bronchiolitis

Who Can Participate

Age: 0Months - 12Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinically diagnosed acute bronchiolitis
  • High flow nasal cannula treatment has lasted for at least 12 hours
  • Measured oxygen saturation of 95% or more on room air
  • High flow rate is a maximum of 2 liters per kilogram per minute
  • Treating doctor considers the infant suitable to stop high flow therapy
Not Eligible

You will not qualify if you...

  • Major congenital anomaly of lungs, heart, or diaphragm
  • Bacterial pneumonia
  • Parents do not give consent

AI-Screening

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Trial Site Locations

Total: 4 locations

1

Siun Sote

Joensuu, Finland

Actively Recruiting

2

Central Finland Hospital District

Jyväskylä, Finland

Actively Recruiting

3

Kuopio University Hospital

Kuopio, Finland

Actively Recruiting

4

Mikkeli Central Hospital

Mikkeli, Finland

Actively Recruiting

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Research Team

I

Ilari Kuitunen, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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