Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06244160

High Flow Oxygen Therapy After Spinal Cord Injury

Led by Cardiff and Vale University Health Board · Updated on 2025-08-05

30

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this feasibility study is to learn about the ability to use a different form of oxygen therapy (known as high flow oxygen therapy) in patients who have a spinal cord injury in the upper back or neck. The main questions it aims to answer are: 1. Is it possible to recruit patients to the study 2. It is possible to follow the protocol in its current format 3. What is the impact on those receiving the intervention. Participants will be randomised to receive either standard care or high flow oxygen therapy for 10 days following inclusion.

CONDITIONS

Official Title

High Flow Oxygen Therapy After Spinal Cord Injury

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Spinal cord injury between C4 and T4 levels including ASIA A-D categories
  • Admission to spinal injury ward within 24 to 48 hours of injury
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • Three or more rib fractures or flail chest
  • Sternal fracture
  • Concomitant lung injury
  • Unable to provide informed consent
  • Contraindications to high flow oxygen therapy such as undrained pneumothorax, facial fractures, nasal obstruction, cerebrospinal fluid leak, suspected or confirmed base of skull fracture, active nosebleed, or recent sinus surgery

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Cardiff and Vale University Health Board

Cardiff, United Kingdom, CF144XW

Actively Recruiting

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Research Team

P

Paul Twose, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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