Actively Recruiting

Age: 18Years +
All Genders
NCT03850015

High Frame Rate Ultrasound in Heart Disease Assessment

Led by London North West Healthcare NHS Trust · Updated on 2025-05-23

25

Participants Needed

1

Research Sites

191 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study will compare standard ultrasound images to high frame rate ultrasound images in patients with heart disease or with a low risk of heart disease to see if a higher frame rate of ultrasound adds to the information obtained from standard ultrasound.

CONDITIONS

Official Title

High Frame Rate Ultrasound in Heart Disease Assessment

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to give informed consent
  • Age 18 years or older
  • Confirmed inducible wall motion or perfusion abnormality on previous stress echocardiogram
  • Known coronary artery disease defined by flow-limiting coronary stenosis (>70% diameter stenosis) on coronary angiography
  • Or patient assessed as low risk of having coronary heart disease
Not Eligible

You will not qualify if you...

  • Inability to undertake pharmacological stress due to known intolerance to dipyridamole
  • Moderate or severe aortic or mitral regurgitation or severe mitral stenosis
  • Significant pulmonary disease such as severe COPD or pulmonary fibrosis
  • Atrial fibrillation
  • Inability to provide informed consent
  • Pregnancy and lactation
  • Known allergy to Sonovue contrast agent
  • Second and third degree heart block unless a pacemaker is fitted
  • Systolic blood pressure less than 90
  • Known Myasthenia Gravis
  • Bronchial asthma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

London North West University Healthcare NHS Trust

Harrow, Middx, United Kingdom, HA1 3UJ

Actively Recruiting

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Research Team

E

Emma Howard, MSc

CONTACT

L

Lasha Gvinianidze, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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High Frame Rate Ultrasound in Heart Disease Assessment | DecenTrialz