Actively Recruiting
High Impact Training to Patients with Prostate Cancer and Bone Metastases
Led by Copenhagen University Hospital at Herlev · Updated on 2025-02-13
102
Participants Needed
1
Research Sites
151 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
HIP is a randomized controlled trial. The aim is investigate the effect, safety and feasibility of brief, high-impact exercise targeting bones in patients with prostate cancer and bone metastases. Furthermore, to investigate the effects of the intervention on bone status (bone mineral density) and body composition, physical function and performance, patient reported quality-of-life outcomes, falls and hospitalizations. The effects of resistance training on the antitumor immunity will be assessed in the peripheral blood and tumor biopsies (HIPimmune).
CONDITIONS
Official Title
High Impact Training to Patients with Prostate Cancer and Bone Metastases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with metastatic hormone sensitive prostate cancer (mHSPC)
- Presence of bone metastases confirmed by recent imaging (Bone scan, CT, MRI, and/or PET)
- Treated with androgen deprivation therapy (ADT) started less than 12 months ago
- Additional treatments like radiotherapy, novel hormone agents, or docetaxel are allowed
- Eastern Cooperative Oncology Group (ECOG) performance status score less than 2
- Able to speak and read Danish and provide signed informed consent
- Ambulatory without walking aids
You will not qualify if you...
- Any physical condition that interferes with performing physical exercise training
- Musculoskeletal, cardiovascular, or neurologic conditions that prevent exercising
- Bone pain requiring opioid treatment
- Planned or prior palliative radiation therapy to the bone
- Major surgery within the past 6 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Herlev and Gentofte Hospital
Herlev, Herlev, Denmark, 2730
Actively Recruiting
Research Team
A
Anne-Mette Ragle, PhD student
CONTACT
P
Peter Busch Østergren, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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