Actively Recruiting
High Intensity Focused Ultrasound Treatment of Breast Tumors. BRIFU Study
Led by Institut Bergonié · Updated on 2025-10-02
15
Participants Needed
1
Research Sites
447 weeks
Total Duration
On this page
Sponsors
I
Institut Bergonié
Lead Sponsor
L
Ligue contre le cancer, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
Monocentric prospective study evaluating the efficacy of High intensity focused ultrasound (HIFU) in breast tumors.
CONDITIONS
Official Title
High Intensity Focused Ultrasound Treatment of Breast Tumors. BRIFU Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically proven invasive ductal carcinoma with hormone receptor, tumor grade, and Her-2 analysis
- Lesions measuring 15 mm or less on ultrasound, unifocal or multifocal, with or without microcalcifications
- Clinical stage N0 breast cancer
- Bra cup size B or larger
- Lesion identifiable and markable on MRI
- Indication for partial or total mastectomy if multifocal or extensive calcifications with axillary surgery
- Breast assessed by mammography, ultrasound, and clinical exam by a radiologist
- No contraindications to MRI
You will not qualify if you...
- Infiltrating lobular carcinoma or pure ductal carcinoma in situ
- Bilateral breast lesions
- Lesions not detectable by MRI, within 10 mm of skin, or larger than 15 mm on ultrasound
- Unifocal palpable tumor
- Bra cup size A
- Skin lesions on breast planned for HIFU treatment
- Unable to maintain required position during treatment for 1 hour
- Pregnant or postpartum patients
- Participation in another interventional clinical trial within 30 days before enrollment or during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Institut Bergonie
Bordeaux, France, 33076
Actively Recruiting
Research Team
J
Jean PALUSSIERE, MD
CONTACT
S
Simone MATHOULIN-PELISSIER, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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