Actively Recruiting
High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study
Led by Dana-Farber Cancer Institute · Updated on 2026-02-24
30
Participants Needed
1
Research Sites
198 weeks
Total Duration
On this page
Sponsors
D
Dana-Farber Cancer Institute
Lead Sponsor
S
Stahl Family Charitable Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to determine whether a 16-week virtual, home-based, high-intensity interval training (HIIT) exercise program will improve physical, cognitive, and emotional health among young adult survivors of pediatric brain tumors. The names of the study interventions involved in this study are/is: * High-Intensity Interval Training (HIIT)
CONDITIONS
Official Title
High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provide written informed consent before starting the study procedures
- Be between 18 and 45 years old at the time of study
- Have a brain tumor diagnosed during childhood or an IDH-mutant glioma diagnosed after age 18
- Be at least 2 years post tumor-directed therapy for pediatric brain tumor survivors or at least 1 year since last surgery, radiation, or chemotherapy for IDH-mutant glioma patients (or assessed able to participate by physician)
- For patients with tumor-related epilepsy, have good seizure control with no generalized seizures in the past 6 months
- Be medically cleared to exercise by a physician or certified clinical exercise physiologist
- Have no other medical conditions that could worsen with exercise, such as bone disease with high fracture risk or uncontrolled heart/lung/metabolic diseases
- Speak English and/or Spanish
- Currently do 60 minutes or less of moderate or vigorous structured exercise per week
- Do not smoke cigarettes or e-cigarettes regularly (social smoking or vaping allowed)
- Be willing to travel to Dana-Farber Cancer Institute for required data collection
- Understand and be willing to sign informed consent
You will not qualify if you...
- Have a primary spinal cord tumor diagnosis
- Have uncontrolled tumor-related epilepsy, cardiopulmonary disease, or metabolic diseases that could worsen with exercise
- Have progressive central nervous system or systemic cancer diagnosed in the last 3 months
- Are pregnant or planning pregnancy during the study period
- Are actively on a weight loss diet
- Participate in more than 60 minutes of moderate or vigorous structured exercise per week
- Currently and regularly smoke cigarettes
- Are unable to travel to Dana-Farber Cancer Institute for required data collection
- Are unlikely to comply with safety monitoring requirements as judged by the investigator
AI-Screening
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Trial Site Locations
Total: 1 location
1
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
C
Christina Dieli-Conwright, PhD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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