Actively Recruiting
High Potency Cannabis: Acute and Protracted Effects
Led by University of California, Los Angeles · Updated on 2025-10-06
30
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
U
University of California, Los Angeles
Lead Sponsor
C
California Department of Cannabis Control (DCC)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research is to assess the effects of smoked cananbis when cannabis is smoked during periods of cannabis use as usual and after a brief period of abstinence.
CONDITIONS
Official Title
High Potency Cannabis: Acute and Protracted Effects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or non-pregnant and non-lactating females aged 21-55 years
- Report cannabis smoking near daily
- Not currently seeking treatment for their cannabis use
- Have a Body Mass Index from 18.5 - 34 kg/m2
- Able to perform all study procedures
- Must be using a contraceptive (hormonal or barrier methods)
You will not qualify if you...
- Meeting DSM-V criteria for any substance use disorder other than cannabis, nicotine, or caffeine
- Negative urine toxicology for cannabis use during screening
- Severe psychiatric illness posing risk or impairing participation
- Use of other illicit drugs within the past 4 weeks
- Current predominant use of medical cannabis, prescription analgesics, or medications affecting study outcomes
- Current pain
- Pregnancy
- Enrollment in another research protocol
- Not using a contraceptive method (hormonal or barrier)
- Insensitivity to cold water in the Cold Pressor Test
- Any disorders making cannabis use hazardous as determined by physician
- Inability to speak and read English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UCLA Center for Cannabis and Cannabinoids
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
Z
Ziva Cooper, PhD
CONTACT
V
Vincent Acebo
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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