High Resolution and High Speed Multimodal Ophthalmic Imaging

What this Trial Is About

Researchers are evaluating advanced ophthalmic imaging techniques to better understand eye conditions that can lead to blindness. This study focuses on using high-resolution and high-speed imaging systems to capture detailed images of eye microstructures like photoreceptors, blood vessels, and nerve bundles. The goal is to observe eye structures that are not visible with standard clinical imaging technologies and improve knowledge of structural changes during eye diseases. The study involves two main imaging approaches: high-resolution retinal imaging through adaptive optics with full-field optical coherence tomography, and retinal imaging using laser Doppler holography. Participants will undergo these imaging procedures, which require placing the forehead and chin on supports while fixing on a test pattern. Each imaging session lasts less than half an hour, with possible repeated acquisitions to cover the desired eye area. The imaging protocols may be adjusted based on the participant’s eye condition and the specific system used. During the study, participants will have their eye structures visualized and the reproducibility of imaging data measured over time, up to five years. The researchers will compare these advanced imaging results with those from routine clinical systems. The study includes both patients with various eye pathologies and healthy volunteers. Participants will be monitored for safety, and the study collects detailed imaging data to evaluate the effectiveness of these new imaging technologies.

High Resolution, High-speed Multimodal Ophthalmic Imaging