Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT04129021

High Resolution, High-speed Multimodal Ophthalmic Imaging

Led by Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts · Updated on 2025-11-18

1200

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems are limited in resolution, speed, or access to certain structures of the eye. The use of a high-resolution imaging system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea. The use of a high-speed acquisition imaging system makes it possible to detect functional measurements such as the speed of blood flow. The combination of data from multiple imaging systems to obtain multimodal information is of great importance for improving the understanding of structural changes in the eye during a disease. The purpose of this project is to observe structures that are not detectable with routinely used systems.

CONDITIONS

Official Title

High Resolution, High-speed Multimodal Ophthalmic Imaging

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • People over 18
  • Patients with an eye pathology or healthy volunteers
  • Participants who have signed consent
  • Beneficiaries of health insurance
Not Eligible

You will not qualify if you...

  • History of photosensitivity
  • Recent photodynamic therapy treatment
  • Use of drugs causing photosensitivity as a side effect
  • Presence of pacemaker or implanted electronic medical device
  • Viral conjunctivitis or other infectious eye disease
  • Skin lesions on neck or forehead
  • High risk of damage from optical radiation (e.g., aphakic patients or decreased light sensitivity due to fundus disease)
  • Pregnant or lactating women
  • Inability to be followed throughout the study
  • Vulnerable individuals
  • Predisposition to closure of the iridocorneal angle

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts

Paris, France, 75012

Actively Recruiting

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Research Team

N

Nabil BROUK

CONTACT

A

Azedine DJABALI

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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