Actively Recruiting
High Resolution Imaging for Analysis of MVNT
Led by Fondation Ophtalmologique Adolphe de Rothschild · Updated on 2026-01-05
33
Participants Needed
7
Research Sites
375 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
MVNT (multinodular and vacuolating neuronal tumor of the cerebrum) is a benign, recently discovered, neuronal lesion, the incidence of which is unknown. It seems to predominate in the temporal lobes and presents a characteristic MRI appearance: multiple subcortical nodules, developed at the white substance / gray substance junction, of variable size, well limited, in iso-hyposignal T1, hypersignal T2 and hypersignal FLAIR. The articles describing this entity report the lack of scalability in MRI during patient monitoring, going in the direction of the benignity of the lesion. The diagnosis sometimes remains uncertain with current MRI sequences, and the patient risks undergoing invasive surgery to remove a lesion that is actually benign. Hence the importance of developing the most precise diagnostic criteria possible. The contribution of advanced MRI techniques, such as ultra-high resolution sequences in the characterization of these lesions, has not yet been studied.
CONDITIONS
Official Title
High Resolution Imaging for Analysis of MVNT
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient over 18 years of age
- Suspected MVNT on a first exploratory MRI with at least 2 major criteria and 1 minor criterion:
- Major criteria: multinodular clustered appearance and frank hypersignal FLAIR/T2
- Minor criteria: no mass effect and hyposignal T1
- Provided informed consent to participate in the study
You will not qualify if you...
- Contraindication to MRI
- Under legal protection measures
- Pregnant or breastfeeding woman
- No characterization MRI done
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Groupe Hospitalier Pellegrin
Bordeaux, Bordeaux, France, 33076
Active, Not Recruiting
2
CHU Rennes
Rennes, Rennes, France, 35033
Actively Recruiting
3
CHU de Rouen
Rouen, Rouen, France, 76000
Active, Not Recruiting
4
Hôpital Pierre Paul Riquet, CHU Purpan
Toulouse, Toulouse, France, 31059
Active, Not Recruiting
5
Fondation A De Rothschild
Paris, France, 75019
Actively Recruiting
6
Centre Hospitalier Lyon Sud
Pierre-Bénite, France, 69495
Active, Not Recruiting
7
Hôpital Laennec
Saint-Herblain, France, 44800
Actively Recruiting
Research Team
A
Amelie YAVCHITZ, PhD
CONTACT
A
Augustin Lecler
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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