Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06822231

High-Tech Rehabilitation Pathway for Acute Adult Neuromuscular Diseases - Fit4MedRob-Acute MND Project

Led by Istituti Clinici Scientifici Maugeri SpA · Updated on 2026-03-03

124

Participants Needed

8

Research Sites

74 weeks

Total Duration

On this page

Sponsors

I

Istituti Clinici Scientifici Maugeri SpA

Lead Sponsor

A

Azienda Ospedaliero-Universitaria di Modena

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is determine if a high-tech rehabilitation circuit is more effective than usual rehabilitation methods in improving functional outcome, particularly balance control, for patients with acute neuromuscolar diseases. The main question it aims to answer is: Are high-tech rehabilitation interventions, including robotic systems, virtual reality, and stabilometric platforms, more effective than traditional rehabilitation methods in improving balance, motor function, fatigue levels, sarcopenia, cognitive engagement, and overall quality of life in patients with acute neuromuscular diseases (NMDs)? Researchers will compare a robotic treatment group, that consists in an high-tech rehabilitation, with a control group, that will receive the traditional rehabilitative treatment.

CONDITIONS

Official Title

High-Tech Rehabilitation Pathway for Acute Adult Neuromuscular Diseases - Fit4MedRob-Acute MND Project

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 80 years
  • Confirmed diagnosis of acute or subacute neuromuscular diseases such as Guillain-Barré Syndrome, Critical Illness Myopathy, or Critical Illness Polyneuropathy
  • Disease onset between 15 and 30 days prior to enrollment
  • Lower limb muscle strength of 2 or more on the Medical Research Council scale in at least two of the flexor and extensor muscles of the hip, knee, and ankle joints
  • Ability to provide informed consent
Not Eligible

You will not qualify if you...

  • Unstable medical conditions that could interfere with safe participation, including severe cardiovascular diseases (NYHA class 4) or uncompensated respiratory distress
  • Participation in other clinical trials that might interfere with this study
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 8 locations

1

Istituti Clinici Scientifici Maugeri

Bari, Italy, 70124

Not Yet Recruiting

2

IRCCS Azienda Ospedaliera Universitaria San Martino - Genova

Genova, Italy, 16132

Not Yet Recruiting

3

Istituti Clinici Scientifici Maugeri IRCCS, Milan Institute

Milan, Italy, 20138

Actively Recruiting

4

Azienda Ospedaliero-Universitaria di Modena

Modena, Italy, 41126

Not Yet Recruiting

5

Istituti Clinici Scientifici Maugeri

Montescano, Italy, 27040

Not Yet Recruiting

6

Istituti Clinici Scientifici Maugeri

Pavia, Italy, 27100

Not Yet Recruiting

7

Fondazione Don Carlo Gnocchi Onlus

Roma, Italy, 00135

Not Yet Recruiting

8

Istituti Clinici Scientifici Maugeri

Telese Terme, Italy, 82037

Not Yet Recruiting

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Research Team

C

Christian Lunetta, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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