Clinical Protocol for a Pragmatic Trial on a High-Tech Rehabilitation Pathway for Chronic Adult Neuromuscular Diseases (Fit4MedRob-Chronic MND Project)

What this Trial Is About

This research aims to evaluate whether a rehabilitation program that uses advanced technologies like robotic systems, virtual reality, and stabilometric platforms is not worse than traditional rehabilitation in reducing fatigue and improving balance, motor skills, and quality of life in adults with chronic neuromuscular diseases such as ALS, CIDP, and Charcot-Marie-Tooth disease. The study is designed as an interventional, randomized, double-blind trial to compare these two rehabilitation approaches. Participants will be assigned to one of two groups: the robotic treatment group or the control group. The robotic group will engage in motor and cognitive exercises using devices such as VRRS EVO for virtual reality, GEA MASTER or PROKIN Technobody platforms for balance training, and Walkerview Technobody robotic treadmills for aerobic exercises, combined with usual physiotherapy. The control group will receive traditional rehabilitation treatments as per standard clinical practice. Treatment effects will be measured over a 60-day period. During the study, participants will undergo various assessments including fatigue severity, walking and mobility tests, quality of life surveys, patient perception questionnaires, and disease-specific functional rating scales at multiple time points from baseline to day 60. Researchers will monitor changes in these measures to determine the impact of the high-tech rehabilitation compared to traditional methods. The total participation time includes multiple visits and evaluations during the study timeline ending in March 2026.

High-Tech Rehabilitation Pathway for Chronic Adult Neuromuscular Diseases - Fit4MedRob-Chronic MND Project