Actively Recruiting
High Versus Low Dose Serratus Anterior Plane Block After Minimally Invasive Valve Surgery.
Led by Jessa Hospital · Updated on 2025-05-14
100
Participants Needed
1
Research Sites
201 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to compare the efficacy and quality of pain relief provided by the high-dose serratus anterior plane (SAP) block with the standard SAP block in preventing and treating acute postoperative pain after total endoscopic aortic or mitral valve surgery.
CONDITIONS
Official Title
High Versus Low Dose Serratus Anterior Plane Block After Minimally Invasive Valve Surgery.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for elective aortic valve surgery or elective mitral valve surgery via right anterolateral thoracotomy
- Adult patients aged 18 years or older
- Bodyweight greater than 50 kilograms
- EuroScore II less than 3%
You will not qualify if you...
- Refusal to participate in the study
- Inability to communicate due to language or neurological barriers
- Inability to use patient-controlled intravenous analgesia or understand pain scoring due to confusion or learning difficulties
- Chronic use of opioids
- Chronic use of analgesic antidepressants or antiepileptic medications
- Use of medications that may interact with bupivacaine-epinephrine or opioids (such as mexiletine, ketoconazole, theophylline, IMAO, Digitalis, or cimetidine)
- History of major trauma or surgery on the right chest wall
- History of chronic pain on the right chest wall
- Allergy to opioids or local anesthetics
- Allergy to paracetamol
- Severe obesity (BMI 40 or more)
- Pregnancy
- Intraoperative events affecting early postoperative recovery (including aortic dissection, systolic anterior motion of the mitral valve, cardiac tamponade, or brady-arrhythmias needing external pacing)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Jessa hospital
Hasselt, Limburg, Belgium, 3500
Actively Recruiting
Research Team
B
Björn Stessel, Dr
CONTACT
I
Ina Callebout, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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