Actively Recruiting
HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men
Led by University of Zurich · Updated on 2025-06-13
270
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
Sponsors
U
University of Zurich
Lead Sponsor
N
National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov
Collaborating Sponsor
AI-Summary
What this Trial Is About
Randomized clinical trial evaluating the effect of acetazolamide on pulmonary artery pressure in women compared to men travelling to 3600 m.
CONDITIONS
Official Title
HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy, non-smoking men and women aged 18 to 44 years without diseases or need of regular medication, including oral contraceptives
- Body mass index (BMI) greater than 18 kg/m2 and less than 30 kg/m2
- Born, raised, and currently living at altitudes below 1000 meters
- Written informed consent provided
- Premenopausal women with a regular menstrual cycle
You will not qualify if you...
- Use of contraceptives other than oral contraceptives, such as hormonal intrauterine devices, vaginal rings, subcutaneous injections, or implants
- Pregnancy or nursing
- Anemia with hemoglobin concentration less than 10 g/dl
- Any trip to altitude within 4 weeks before the study
- Allergy to acetazolamide or other sulfonamide drugs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Center for Cardiology and Internal Medicine
Bishkek, Bishkek, Kyrgyzstan, 720040
Actively Recruiting
Research Team
S
Silvia Ulrich, Prof. Dr.
CONTACT
T
Talant Sooronbaev, Prof. Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
4
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