Actively Recruiting

Phase 4
Age: 18Years - 44Years
All Genders
Healthy Volunteers
NCT06498531

HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men

Led by University of Zurich · Updated on 2025-06-13

270

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

Sponsors

U

University of Zurich

Lead Sponsor

N

National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov

Collaborating Sponsor

AI-Summary

What this Trial Is About

Randomized clinical trial evaluating the effect of acetazolamide on sleep disordered breathing in women compared to men travelling to 3600 m.

CONDITIONS

Official Title

HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men

Who Can Participate

Age: 18Years - 44Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy, non-smoking men and women aged 18 to 44 years without diseases or regular medications, including oral contraceptives
  • Body mass index between 18 and 30 kg/m2
  • Born, raised, and currently living at altitudes below 1000 meters
  • Provided written informed consent
  • Premenopausal women with a regular menstrual cycle
Not Eligible

You will not qualify if you...

  • Use of contraceptives other than oral contraceptives (e.g., hormonal intrauterine device, vaginal ring, subcutaneous injections or implants)
  • Pregnancy or nursing
  • Anemia with hemoglobin concentration below 10 g/dl
  • Any altitude trip within 4 weeks before the study
  • Allergy to acetazolamide or other sulfonamides

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Center for Cardiology and Internal Medicine

Bishkek, Bishkek, Kyrgyzstan, 720040

Actively Recruiting

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Research Team

M

Michael Furian, Prof. Dr.

CONTACT

T

Talant Sooronbaev, Prof. Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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