Actively Recruiting
Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants
Led by Prince of Songkla University · Updated on 2024-09-19
120
Participants Needed
1
Research Sites
195 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized clinical trial is to compare the effect of higher (10 mg per day) versus standard (1 mg per day) doses of zinc supplementation The main questions it aims to answer are: * Growth velocities and delta z-scores during the date of start intervention until the end of the time interval (at least 2 weeks of intervention on date of 44 weeks of postmenstrual age or discharge whichever came first) in very preterm infants with a birthweight less than1800 grams. * Growth and neurodevelopment at 24 months postnatal age
CONDITIONS
Official Title
Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Very preterm neonates (gestational age 24 0/7-32 6/7 weeks) admitted consecutively in the NICU and NMCU
- Birth weight between 401 and 1800 grams
- Body weight at enrollment less than 800 grams
- Stable neonates and receiving full enteral feeding (150 mL/kg/day) for at least a few days
You will not qualify if you...
- Outborn neonates admitted to the study center after 7 days of life
- Congenital infections
- Malformations, syndromes, or genetic defects
- Proven sepsis, necrotizing enterocolitis, or death before enrollment
- Gastrointestinal surgery or high gastrointestinal fluid output
- Unstable neonates during weighing or with chest drainage
- Neonates requiring diuretics for more than 7 days
- Severe birth asphyxia (5-minute Apgar score less than 4)
- Parents' decision not to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Songklanagarind Hospital, Prince of Songkla University
Hat Yai, Changwat Songkhla, Thailand, 90110
Actively Recruiting
Research Team
A
Anucha Thatrimontrichai, MD
CONTACT
B
Boonwiroj Jitwilertrat, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here