Actively Recruiting

All Genders
NCT06742073

Histiocytosis and Inflammatory Manifestations in Patients with H Syndrome

Led by Rabin Medical Center · Updated on 2024-12-19

120

Participants Needed

1

Research Sites

91 weeks

Total Duration

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AI-Summary

What this Trial Is About

H syndrome is a rare genetic disorder predisposing to histiocytosis. Our knowledge of the clinical spectrum of these patients is based on case reports and small patient series. Patients with H syndrome have been treated with a range of immunomodulatory and chemotherapeutic agents, with limited success. We aim to comprehensively assess the clinical manifestations and patterns of treatment response in a multinational cohort of patients with H syndrome.

CONDITIONS

Official Title

Histiocytosis and Inflammatory Manifestations in Patients with H Syndrome

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Any patient with a genetically confirmed diagnosis of H syndrome
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Schneider Children's Medical Center

Petah Tikva, Israel

Actively Recruiting

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Research Team

S

Sarah Elitzur, MD

CONTACT

N

Naomi Litichever, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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