Actively Recruiting
HIV Prevention With PrEP Among People on Opioid Replacement Therapy
Led by Cara Spence · Updated on 2025-10-07
350
Participants Needed
6
Research Sites
104 weeks
Total Duration
On this page
Sponsors
C
Cara Spence
Lead Sponsor
G
Gilead Sciences
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to assess the feasibility and acceptability of providing oral pre-exposure prophylaxis (PrEP) and opioid agonist therapy (OAT) simultaneously in existing pharmacy-based programs operating in Alberta and Saskatchewan, to collect preference, adherence, and persistence data on oral PrEP, and to assess interest / acceptability of long-lasting injectable options for human immunodeficiency virus (HIV) prevention.
CONDITIONS
Official Title
HIV Prevention With PrEP Among People on Opioid Replacement Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- HIV negative
- Ongoing behaviors with potential HIV exposure as assessed by a clinician
- Regularly engaged with their respective OAT program at least 3 days a week for the past 2 weeks
- Report willingness to return for follow-up visits
You will not qualify if you...
- Creatine clearance less than 30 mL/min or any medical condition or medication known to be contraindicated with the use of Emtricitabine/Tenofovir Alafenamide (F/TAF) or Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF)
- Taken PrEP within the last 24 hours at the time of screening or enrollment
- Deemed appropriate by a clinician for HIV Post-Exposure Prophylaxis at the time of screening or enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Sheldon M Chumir Health Centre
Calgary, Alberta, Canada, T2R 0X7
Not Yet Recruiting
2
Queen City Wellness Pharmacy
Regina, Saskatchewan, Canada, S4P 0H7
Not Yet Recruiting
3
Mayfair Drugs Pharmacy
Saskatoon, Saskatchewan, Canada, S7L 0V8
Actively Recruiting
4
Pharmasave Riversdale Pharmacy
Saskatoon, Saskatchewan, Canada, S7M 0Y2
Actively Recruiting
5
The Medicine Shoppe Pharmacy
Saskatoon, Saskatchewan, Canada, S7M 0Z7
Actively Recruiting
6
Meadowgreen Pharmacy
Saskatoon, Saskatchewan, Canada, S7M 4R5
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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