HIV Self-testing for Partners of HIV-uninfected Postpartum Women to Facilitate PrEP and Antiretroviral Therapy Uptake to Promote HIV Treatment and Prevention

What this Trial Is About

This research aims to evaluate a combination intervention called H4P to support HIV self-testing for partners and promote PrEP uptake among HIV-uninfected postpartum women who have partners with unknown HIV status. The study focuses on postpartum women and their male partners in KwaZulu-Natal, South Africa, using evidence-based cognitive behavioral therapy strategies like communication skills training, motivational interviewing, and problem-solving. This pilot trial will assess how feasible and acceptable the intervention is and explore its early effects on PrEP use and HIV prevention. Participants include postpartum women between 30 and 40 weeks' gestation and their male partners. Women in the control group receive up to three HIV self-test kits with standard information and demonstrations for their partners. Those in the intervention group receive additional 30-45 minute counseling covering PrEP information and skills to support HIVST kit distribution and linkage to care. Male partners in the intervention group watch a video about HIV treatment resources and the importance of HIV care in their relationship. Both groups receive HIV self-test kits and instructions for use. Participants will be followed at baseline and three months, completing assessments on feasibility, acceptability, safety concerns from HIVST distribution, and preliminary effectiveness of the intervention. Measures include PrEP uptake, HIV and pregnancy characteristics, physical and mental health, substance use, relationship dynamics, partner violence, stigma, and barriers to care. Women and men must provide consent and participate in repeated assessments. The total participation duration is at least three months after enrollment.

HIV Self-testing for Partners of HIV-uninfected Postpartum Women