Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07194902

HIV Self-testing for Partners of HIV-uninfected Postpartum Women

Led by Massachusetts General Hospital · Updated on 2026-03-23

120

Participants Needed

1

Research Sites

23 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to test the feasibility and acceptability of a combination intervention to promote HIV self-testing (HIVST) for Partners and PrEP uptake for HIV-uninfected Postpartum Women ("H4P"). H4P includes evidence-based cognitive behavioral therapy (CBT) strategies, such as communication skills training, motivational interviewing, and problem-solving. The investigators will conduct a randomized pilot trial of the H4P intervention to evaluate the feasibility, acceptability, and preliminary effectiveness of a multi-step PrEP uptake and HIV self-test kit intervention for postpartum HIV-uninfected women (N = 60 and their male partners) who report a partner of unknown serostatus, and their partners, in the province of KwaZulu-Natal, South Africa.

CONDITIONS

Official Title

HIV Self-testing for Partners of HIV-uninfected Postpartum Women

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Woman aged 18 years or older
  • At least 30 weeks pregnant according to medical records
  • Negative HIV test in the third trimester confirmed by antenatal care chart
  • Reporting at least one partner with unknown HIV status
  • Fluent in English or isiZulu
  • Willing to give permission for repeated researcher contact
  • Able to provide informed consent
  • Male partners must be 18 years or older
  • Male partners must be confirmed partners of enrolled women through verification
  • Male partners fluent in English or isiZulu
  • Male partners willing to give permission for researcher contact
  • Male partners able to provide informed consent
Not Eligible

You will not qualify if you...

  • Significant psychiatric illness that may interfere with participation or informed consent, as determined by the study team

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Wits MatCH Research Unit

Durban, KwaZulu-Natal, South Africa

Actively Recruiting

Loading map...

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here