Actively Recruiting
HOBSCOTCH-CA (Home-Based Self-Management and Cognitive Training Changes Lives in Brain Cancer)
Led by Dartmouth-Hitchcock Medical Center · Updated on 2025-11-21
125
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
Sponsors
D
Dartmouth-Hitchcock Medical Center
Lead Sponsor
C
Congressionally Directed Medical Research Programs
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the HOBSCOTCH-CA program, a home-based intervention designed to improve quality of life and cognitive function in Service Members, Veterans, and civilians who have survived brain cancer or brain tumors. The study also aims to assess how this program might reduce caregiver burden and enhance caregivers' quality of life. The intervention adapts problem-solving therapy to address the cognitive challenges faced by these patients and their caregivers. Participants will be randomly assigned to one of two groups. Group 1 receives the HOBSCOTCH-CA program immediately, while Group 2 waits for three months before starting the intervention. The program includes an initial pre-session and eight weekly sessions conducted virtually, including educational sessions and telephone or webcam follow-ups. Caregivers who choose to enroll receive a tailored version of the program with fewer sessions, focusing on education and mindfulness. Throughout the approximately six-month study, participants will complete questionnaires and surveys at enrollment, three months, and six months. They will also engage in daily diaries on a smartphone app, tracking symptoms, medication adherence, memory strategies, and well-being. Researchers will measure changes in quality of life, cognition, caregiver burden, mood, anxiety, and satisfaction with the program. The study involves regular virtual coaching sessions and continuous monitoring of participants and caregivers.
CONDITIONS
Brief Title
HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Service members, Veterans, and civilians diagnosed with brain cancer (excluding glioblastoma)
- Diagnosis of a primary brain tumor with expected survival of 2 years or more (e.g., low-grade glioma, oligodendroglioma, IDH mutant astrocytoma, meningioma) confirmed by imaging or pathology
- Completed surgical and/or radiation therapy at least 3 months before enrollment
- Stable on all central nervous system acting medications for at least one month prior to enrollment
- Have subjective cognitive complaints
- Literate and proficient in English
- Access to internet for video sessions and telephone for other sessions
- Caregivers aged 18 or older may enroll with participant's permission (optional)
You will not qualify if you...
- Presence of neurodegenerative disease such as Alzheimer's or Parkinson's disease
- Acute psychiatric disorder or substance abuse
- Diagnosis of glioblastoma (GBM)
- Caregivers with significant visual impairment preventing reading or writing
- Caregivers without reliable telephone or internet access
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote)
Duration - 1 to 2 weeks
Participants complete baseline assessments before starting the intervention.
1 visit (in-person or remote)
Duration - 8 weeks
Participants receive the HOBSCOTCH-CA intervention through weekly sessions including pre-intervention, educational, telephone/webcam sessions, and wrap-up sessions focused on cognitive self-management and quality of life improvements.
Weekly sessions for 8 weeks (combination of webcam and telephone visits)
Duration - Up to 6 months post-intervention
Participants complete follow-up assessments at 3 months and 6 months post-intervention to evaluate quality of life, cognitive function, caregiver burden, and other health outcomes.
2 visits (at 3 months and 6 months post-intervention, remote or in-person)
Trial Site Locations
Total: 1 location
1
Dartmouth-Health Lebanon
Lebanon, New Hampshire, United States, 03756
Actively Recruiting
Research Team
S
Sarah J. Kaden, BA
T
Trina K Dawson, BA
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
4
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