Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06291922

Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

Led by University of Pennsylvania · Updated on 2025-09-26

100

Participants Needed

4

Research Sites

202 weeks

Total Duration

On this page

Sponsors

U

University of Pennsylvania

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate the effects of a home-based exercise program using mobile technology on physical activity and capacity, frailty and muscle mass, and quality of life in patients with a newly implanted HeartMate 3 left ventricular assist device (HM3 LVAD). Researchers will compare the effects of an exercise intervention vs. usual care on physical activity and capacity, frailty and muscle mass, and quality of life.

CONDITIONS

Official Title

Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Newly implanted with a HeartMate 314 LVAD for the first time
  • Able to walk independently, with or without an assistive device
  • Owns a smartphone with an Internet connection
  • Will be discharged home with LVAD or living at home with LVAD within 45 days of hospital discharge
Not Eligible

You will not qualify if you...

  • Major health problems or limitations that could interfere with exercise, including significant orthopedic or neurologic issues
  • Decompensated heart failure
  • Uncontrolled irregular heart rhythms
  • Unstable angina

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Henry Ford Health

Detroit, Michigan, United States, 48202

Actively Recruiting

2

Cleveland Clinic Foundation

Cleveland, Ohio, United States, 44195

Actively Recruiting

3

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

4

University of Utah Health

Salt Lake City, Utah, United States, 84112

Actively Recruiting

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Research Team

C

Clinical Research Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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