Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT05849532

Home-based FES Training in People With Chronic Stroke

Led by University of Illinois at Chicago · Updated on 2025-09-19

30

Participants Needed

1

Research Sites

172 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project will examine the feasibility, safety and effect of home-based functional electrical stimulation (FES) applied to different lower limb muscles in combination with task-specific training on gait, balance and mobility in adults with chronic stroke. 30 individuals with chronic stroke will first undergo initial screening and baseline walking, mobility, balance and strength assessments in the laboratory. After determining their eligibility for the study, they will undergo 12-weeks of home-based FES and task-specific training. Following the initial screening (week 1) and pre-intervention assessment (week 2), participants will be trained in the lab for 6 sessions (week 3-4) for a FES home program and then given a FES home kit (FES device and an android tablet). Participants will then undergo home-training for 2 weeks (week 5-6) followed by mid-training assessment (week 7). Again, participants will undergo 4-weeks of home training (week 8-11) and final assessment at the end of training (week 12). This project has the following specific aims: Aim 1: To investigate the feasibility, safety and efficacy of 12-weeks of home-based FES and task-specific training in adults with chronic stroke. Aim 2: To examine the effect of 12-weeks of home-based FES and task-specific training on mobility, gait and balance (anticipatory and reactive balance) in adults with chronic stroke.

CONDITIONS

Official Title

Home-based FES Training in People With Chronic Stroke

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 90 years
  • Unilateral weakness on one side of the body (hemiparesis)
  • Stroke occurred more than 6 months ago
  • Able to walk independently at least 300 feet, with or without assistive device
  • Able to understand, speak, and describe pain or discomfort in English
  • Use a smartphone daily
  • Have internet or Wi-Fi access at home
Not Eligible

You will not qualify if you...

  • Body weight over 250 pounds
  • Osteoporosis detected by heel bone density ultrasound (T-score less than -2)
  • Cognitive impairment (Montreal Cognitive Assessment score below 26 out of 30)
  • Verbal aphasia with less than 71% score on Mississippi Aphasia Screening
  • Severe depression (Geriatric Depression Scale score over 15)
  • Any neurological condition other than stroke
  • Uncontrolled or untreated high or low blood pressure, diabetes, or musculoskeletal, neuromuscular, or systemic diseases
  • Recent major surgery within 6 months or hospitalization within 3 months
  • History of deep vein thrombosis
  • Past or current active cancer
  • Peripheral nerve injury or neuropathy causing motor disability in the affected limb
  • Uncontrolled high blood pressure or angina
  • Skin conditions that do not tolerate FES therapy
  • History of epilepsy or other seizure disorders
  • Botox treatment within the last 5 months
  • Use of a pacemaker

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Illinois at Chicago

Chicago, Illinois, United States, 60612-4225

Actively Recruiting

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Research Team

R

Rudri Purohit, MS

CONTACT

J

Jessica Pitts, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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