Video Consultation and Mitochondrial Myopathies: Study of Efficacy and Tolerance of a Personalized Training Program at Home

What this Trial Is About

Researchers are studying the effects of a personalized training program for patients with mitochondrial myopathies, a condition causing exercise intolerance, muscle weakness, and fatigue. The goal is to understand how a mixed training program combining endurance and muscle strengthening, tailored for each patient and conducted at home, can improve physical abilities without worsening certain biological markers. This research aims to provide practical, home-based exercise guidance supported by video consultations, addressing the current lack of clear training recommendations for these patients. Participants will follow a personalized mixed training program at home, which includes both endurance and muscle reinforcement exercises. They will be monitored remotely through video consultations to ensure proper support and guidance. The study tracks their progress over a period from 6 months to 12 months, assessing the effects of training on muscle strength, endurance, functional mobility, and other clinical parameters. During the study, participants will undergo various assessments at 6, 9, and 12 months to measure changes in functional capacity, muscle strength and endurance, walking ability, and quality of life. Researchers will also monitor biological markers such as heteroplasmy levels and creatine phosphokinase to evaluate the safety and tolerance of the training. The study includes questionnaires about physical activity and tiredness to understand participants' condition and the training's impact.

Home Based Personalized Training and Video Consultation in Mitochondrial Myopathies: Study of Efficacy and Tolerance.