What motivates bladder cancer patients to be active? A qualitative study assessing attitudes towards physical activity and digital health technologies.
Alex Zhu, Jessica Sher, Richard Li...
https://pubmed.ncbi.nlm.nih.gov/40441948Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
ID06040762
The Get Moving Trial: A Phase I/II Randomized Study of Home-Based Prehabilitation Using ExerciseRx for Bladder and Upper Tract Urothelial Cancer Surgery
Led by University of Washington · Updated on 2026-03-02
128
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
B
Bladder Cancer Advocacy Network
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to study the benefits of a personalized home-based exercise program to improve physical function and surgical outcomes in patients with bladder cancer and upper tract urothelial carcinoma undergoing major surgery such as radical cystectomy or nephroureterectomy. The trial focuses on patients with these cancers who may also receive chemotherapy before surgery. Improving physical activity before surgery might help reduce inactivity and physical decline after the operation. Participants are randomly assigned to one of two groups. One group uses the ExerciseRx app to perform four 20-30 minute home exercise sessions per week, including core strength and balance exercises, along with personalized step goals, starting at least 4 weeks before surgery and continuing for 90 days after surgery. These patients also wear a FitBit and use its app. The other group receives standard educational materials and wears a FitBit with its app but does not follow the exercise program. Both groups may receive chemotherapy as part of their standard care before surgery. Throughout the study, patients are followed from enrollment through surgery and for 90 days afterward, totaling about 4 to 7 months. Researchers measure changes in physical function, frailty, body composition, patient-reported quality of life, and surgical outcomes such as length of hospital stay and complications. The study also tracks how well patients stick to the exercise program and their experience using the ExerciseRx app, with monitoring via FitBit devices and questionnaires. Surgical outcomes and safety are carefully observed during this period.
CONDITIONS
Brief Title
A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- English-speaking
- Planned treatment with radical cystectomy or radical nephroureterectomy/ureterectomy with or without preceding systemic therapy
- Enough time to complete at least 4 weeks of exercises before surgery if in the exercise group
- Willing and able to participate in trial activities
You will not qualify if you...
- Cognitive or memory impairment preventing ability to follow exercise instructions
- Immobility or inability/unwillingness to perform home exercise safely
- Neurologic or orthopedic conditions restricting unsupervised home exercise
- Nonmuscle-invasive urothelial cancer or metastatic disease including brain metastases
- Predominant histology other than urothelial carcinoma not suitable for surgery
- Uncontrolled or active illness limiting study compliance
- Pregnancy
- Inability to understand or read English
- Lack of access to a compatible Android or iOS smart device
- Not receiving surgery at University of Washington Medical Center
- Participation in another clinical trial that prohibits enrollment in this study
AI-Screening
AI-Powered Screening
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1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Prehabilitation and Monitoring
Duration - 4 to 6 weeks before surgery
Participants begin at least 4 weeks prior to surgery. Arm A participants use the ExerciseRx app for four 20-30 minute home exercise sessions per week plus personalized step count goals, while Arm B participants receive standard educational materials. All participants wear a FitBit and use the FitBit app during this period while receiving standard chemotherapy if applicable.
Weekly remote monitoring visits
Surgery
Duration - Surgery day
Participants undergo standard of care surgery for bladder or upper tract urothelial cancer following the prehabilitation or standard care period.
1 visit (in-person)
Post-surgery Follow-up
Duration - 90 days after surgery
Participants are followed for 90 days after surgery to assess recovery, physical function, and any complications. Arm A participants continue to use the ExerciseRx app and wear the FitBit during this time.
Approximately 3 monthly visits plus ongoing remote monitoring
Trial Site Locations
Total: 1 location
1
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States, 98109
Actively Recruiting
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Research Team
G
Get Moving Research Coordinator
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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