Actively Recruiting
A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial
Led by University of Washington · Updated on 2026-03-02
128
Participants Needed
1
Research Sites
175 weeks
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
B
Bladder Cancer Advocacy Network
Collaborating Sponsor
AI-Summary
What this Trial Is About
Prehabilitation refers to the process of improving a patient's functional capabilities prior to a surgical procedure with the goal of decreasing post-surgical inactivity and physical decline. This clinical trial evaluates the utility of a personalized home-based prehabilitation exercise intervention for the improvement of physical function and surgical outcomes in patients with urothelial carcinoma undergoing definitive or consolidative surgery of the bladder (radical cystectomy) or upper tract (nephroureterectomy, ureterectomy) with or without preceding neoadjuvant/systemic therapy. The exercise intervention includes at-home exercise sessions focused on the improvement of core strength and balance as well as personalized step count goals, delivered to patients remotely via a smart-device-based application (ExerciseRx). Encouraging physical activity before surgery may improve physical function and surgical outcomes in patients who are scheduled to undergo surgery for their bladder or urothelial cancer.
CONDITIONS
Official Title
A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- English-speaking
- Planned treatment with radical cystectomy or radical nephroureterectomy/ureterectomy with or without preceding systemic therapy with enough time to complete at least 4 weeks of exercises before surgery if in the exercise arm
- Willing and able to participate in trial activities
You will not qualify if you...
- Cognitive or memory impairment preventing ability to follow exercise instructions
- Immobility or inability/unwillingness to perform personalized home exercises safely
- Neurologic or orthopedic conditions restricting unsupervised home exercises
- Nonmuscle-invasive urothelial cancer expecting organ-preserving treatments or metastatic disease involving other organs
- Predominant histology other than urothelial carcinoma not candidates for standard surgery
- Uncontrolled or active illness limiting study compliance
- Pregnancy
- Inability to understand or read English
- Lack of access or insufficient facility to use a compatible smart device
- Not receiving surgery at the study center (UWMC)
- Participation in another clinical trial that prohibits enrollment in this trial
AI-Screening
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Trial Site Locations
Total: 1 location
1
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States, 98109
Actively Recruiting
Research Team
G
Get Moving Research Coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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