Actively Recruiting

Phase Not Applicable
Age: 18Years - 89Years
All Genders
NCT06106984

Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations

Led by VA Office of Research and Development · Updated on 2025-10-29

36

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Nearly 60-85% of Veterans with amputations experience pain at the location of the amputated limb called phantom limb pain (PLP). PLP is a major problem and can have a profound impact on Veteran's daily function and ability to fully participate in life. Although several rehabilitation interventions are promising, advances in novel rehabilitation interventions are limited. The objective of this project is to refine a mobile app for graded motor imagery in 12 Veterans with amputations and test the mobile app with 36 Veterans with amputations. For this pilot project, the investigators will measure the preliminary feasibility and acceptability of the intervention. Knowledge from this project will provide evidence to guide future larger studies of this graded motor imagery intervention. Developing novel strategies for chronic pain in this population will positively impact quality of life for Veterans with amputations.

CONDITIONS

Official Title

Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations

Who Can Participate

Age: 18Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Must be a military Veteran
  • At least 18 years old
  • More than 1 year since unilateral below knee amputation
  • Moderate or severe phantom limb pain with a score of 4 or higher on a 0-10 scale
  • Medications stable for at least 2 weeks
  • Willing and able to give informed consent
  • Able to participate in telehealth activities using a personal device
Not Eligible

You will not qualify if you...

  • Unstable medical conditions such as uncontrolled diabetes or heart failure exacerbation
  • Unstable mental illness or substance use disorder including active suicidality or psychosis
  • Unable to give informed consent due to cognitive impairment
  • Fibromyalgia or complex regional pain syndrome-like symptoms

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Minneapolis VA Health Care System, Minneapolis, MN

Minneapolis, Minnesota, United States, 55417-2309

Actively Recruiting

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Research Team

T

Tonya L Rich, PhD MA BS

CONTACT

A

Andrew H Hansen, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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