Actively Recruiting
Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease
Led by The University of Texas Health Science Center at San Antonio · Updated on 2026-02-11
16
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center at San Antonio
Lead Sponsor
H
Huntington's Disease Society of America
Collaborating Sponsor
AI-Summary
What this Trial Is About
The researchers hope to find out effects of transcranial direct current stimulation (tDCS) sessions on the behavioral symptoms of Huntington's Disease. If participants are eligible to continue, they will be provided a device to administer the tDCS for 30 minutes each day and be asked to answer questions with the study staff . Participants will be asked to return to the study center for follow ups and to undergo additional cognitive tests and questionnaires. Participants will also be asked to answer questionnaires via a web conferencing platform (Zoom) during the course of the study. Caregivers of the participants will be asked to answer questionnaires to collect more information about the participants.
CONDITIONS
Official Title
Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 85 years
- Confirmed Huntington's disease mutation or established family history with typical HD symptoms
- Early or moderate disease stages according to Shoulson-Fahn criteria
- Mild to moderate behavioral symptoms without severe symptoms
- Stable medication doses for at least one month
- Ability and willingness to provide written informed consent
- Have a caregiver willing to be present during sessions and answer questionnaires
- Caregiver is an adult unpaid helper with adequate cognitive and communication abilities
You will not qualify if you...
- Unstable medical conditions such as unstable angina, uncontrolled diabetes or hypertension, advanced cancer
- History of epilepsy
- Clinical diagnosis of major cognitive disorder (dementia)
- Risk of suicidal behavior or ideation of specific severity in the past 3 months
- Active participation in another therapeutic clinical trial
- Inability to provide consent
- Presence of pacemaker or other implanted devices contraindicated with tDCS
- Caregiver not meeting inclusion criteria
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States, 78229
Actively Recruiting
Research Team
T
Thiago Macedo e Cordeiro, MD, MSc
CONTACT
A
Antonio L Teixeira, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
DEVICE_FEASIBILITY
Number of Arms
2
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