Actively Recruiting
Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain
Led by Yale University · Updated on 2026-04-13
80
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
Sponsors
Y
Yale University
Lead Sponsor
F
Florida State University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn the feasibility and safety of using home-based taVNS in young adults with IBS to manage their IBS-related pain and symptoms. It will also learn about participants' experience in using the home-based taVNS intervention. The main questions it aims to answer are: * Is it feasible to use a home-based taVNS intervention for pain and symptom management among YAs with IBS? * Is it safe and reported satisfactory to use a home-based taVNS intervention for pain and symptom management among YAs with IBS? Researchers will compare Active to Sham taVNS (a look-alike intervention that contains minimal stimulation) to see if Active taVNS works on managing IBS-related pain and symptoms. Participants will: * Take Active or Sham taVNS intervention for a 6-week treatment (twice daily, 30 minutes per session) * Visit the research lab at the initial setup and the end of the 6-week treatment for checkups and tests * Keep a diary of their symptoms and the number of times they use the taVNS.
CONDITIONS
Official Title
Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 29 years of age
- Men and women
- Diagnosis of IBS by a healthcare provider with current pain
- Moderate pain (3 or higher on numeric rating scale) at least 4 days per week for past 3 months
- Daily access to a computer with internet
- Able to read and speak English
You will not qualify if you...
- Other chronic pain conditions
- Celiac disease or inflammatory bowel disease
- Diabetes mellitus
- Severe psychiatric condition requiring inpatient treatment in past 6 months
- Pregnancy or lactation
- Regular use of opioids or illicit substances
- Use of probiotics or antibiotics within 2 weeks before enrollment
- Conditions preventing taVNS use, including cardiovascular disorders, recent ear trauma, or metal implants above the neck
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Yale University
New Haven, Connecticut, United States, 06511
Actively Recruiting
Research Team
X
Xiaomei S Cong, PhD
CONTACT
J
Jie Chen, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here