Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05771597

Home Biofeedback Therapy for Dyssynergic Defecation, Fecal Incontinence and Urinary Incontinence

Led by Augusta University · Updated on 2023-03-16

72

Participants Needed

1

Research Sites

196 weeks

Total Duration

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AI-Summary

What this Trial Is About

Biofeedback therapy is an effective treatment for the management of patients with dyssynergic defecation and constipation, urinary incontinence (UI), and fecal incontinence (FI). It is labor-intensive, costly, requires multiple office or hospital visits, is not easily available to the vast majority of patients in the community, and is not covered by many insurance companies. The purpose of this study is to 1. Evaluate home biofeedback therapy for patients with either constipation and dyssynergic defecation or urinary leakage or stool leakage by assessing the efficacy and safety of a wireless anorectal biofeedback device, and a cellphone app-based and voice guided home biofeedback training system 2. To compare the efficacy and safety of home biofeedback therapy system with the standard of care, office biofeedback therapy 3. To assess the cost-effectiveness of home biofeedback therapy.

CONDITIONS

Official Title

Home Biofeedback Therapy for Dyssynergic Defecation, Fecal Incontinence and Urinary Incontinence

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • For constipation and dyssynergic defecation: meet Rome IV criteria for functional constipation with symptoms for at least 6 months
  • Have a dyssynergic pattern of defecation confirmed by anorectal manometry and related tests
  • For fecal incontinence: have recurrent episodes for at least 6 months and report at least one episode per week on a stool diary
  • For urinary incontinence: have recurrent episodes for at least 3 months with at least 2 episodes recorded on a urinary incontinence diary
Not Eligible

You will not qualify if you...

  • Structural or metabolic diseases causing constipation based on colonoscopy or imaging and blood tests
  • Use of opioids within the past 2 weeks (unless stable dose over 3 months for incontinence patients)
  • Severe cardiac, renal, or pulmonary disease
  • Neurological diseases such as multiple sclerosis or stroke
  • Rectal prolapse or active anal fissures
  • Alternating constipation and diarrhea pattern
  • Severe diarrhea with Bristol Stool consistency type 6 or higher (for fecal incontinence patients)
  • Active depression
  • Ulcerative or Crohn's colitis
  • Continuous urine leakage (for urinary incontinence patients)
  • Pregnant women or nursing mothers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Augusta University

Augusta, Georgia, United States, 30912

Actively Recruiting

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Research Team

S

Satish Rao, MD, PhD

CONTACT

B

Bianca Marsh, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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