Actively Recruiting

Age: 18Years +
All Genders
NCT06597240

Home Monitoring During Chemoradiation

Led by University Medical Center Groningen · Updated on 2025-08-14

30

Participants Needed

1

Research Sites

72 weeks

Total Duration

On this page

Sponsors

U

University Medical Center Groningen

Lead Sponsor

S

Siemens Corporation, Corporate Technology

Collaborating Sponsor

AI-Summary

What this Trial Is About

Chemoradiotherapy is part of standard treatment for patients with locally advanced oesophageal cancer. Some patients with oesophageal cancer treated with chemoradiotherapy do not complete treatment due to toxicity, or face complications after treatment. Therefore, there is a need for better tools for assessing patients' fitness for chemoradiotherapy and to pick up early signals of deteriorating overall physical condition and complications during and after treatment to timely implement supportive care measures. Tools enabling monitoring physical activity, vital parameters and creatinine concentration in the blood at home are available but have not yet been implemented in patients undergoing chemoradiotherapy for oesophageal cancer. The feasibility and added value remain unknown.

CONDITIONS

Official Title

Home Monitoring During Chemoradiation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older at the time of signing informed consent
  • Histologically proven adenocarcinoma, squamous cell carcinoma, or mixed type of the oesophagus or gastro-oesophageal junction
  • Indication for definitive or neoadjuvant chemoradiotherapy with weekly carboplatin and paclitaxel
  • Written informed consent
  • Ability to comply with all protocol-required actions, including performing home measurements independently
Not Eligible

You will not qualify if you...

  • Altered mental status or any psychiatric condition that would prevent understanding or giving informed consent or performing home measurements

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Medical Center Groningen

Groningen, Netherlands, 9713 GZ

Actively Recruiting

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Research Team

R

Rudolf S.N. Fehrmann, MD, PhD

CONTACT

S

Sjoukje F. Oosting, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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