Actively Recruiting

Age: 12Years +
All Genders
ID06702579

Qualitative Study on Home Monitoring of Hemostasis in Anticoagulant Treatment and Hemophilia A

Led by Radboud University Medical Center · Updated on 2024-11-25

30

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are exploring the potential effects of home monitoring of blood clotting factors in patients with hemophilia A and those on anticoagulant therapy. This observational, cross-sectional study aims to gather insights into the unmet needs of these patients and how home monitoring could impact their care and independence. The study also involves healthcare providers to understand their expectations of home monitoring in hemophilia care. The study includes semi-structured interviews and focus groups involving about 10 patients on vitamin K antagonists who self-monitor coagulation at home, approximately 20 patients with hemophilia A receiving prophylactic treatment, and healthcare professionals experienced in hemophilia care. Participants will share their experiences with current treatment and self-monitoring, and discuss key features for a home monitoring platform. The study does not involve any investigational treatments or interventions. Participants will engage in interviews and focus groups at enrollment to discuss their experiences and expectations regarding home monitoring. Researchers will assess themes related to burdens, unmet needs, and consequences of home self-monitoring. The study aims to identify how home monitoring might improve patient autonomy and care quality. There are minimal risks associated with participation, and minor patients require consent from both themselves and their caregivers. The study is expected to conclude by November 2025.

CONDITIONS

Brief Title

Home Monitoring in Hemophilia a

Who Can Participate

Age: 12Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged over 16 years using vitamin K antagonists for any reason
  • Patients self-testing INR at home for more than 3 months
  • Patients with congenital hemophilia A, with or without inhibitors, receiving prophylactic treatment
  • Patients aged 12 years or older or caregivers of patients younger than 12 years
  • Healthcare providers such as hematologists, hemophilia nurses, or pharmacists involved in hemophilia care with over 3 years of experience
  • Signed informed consent form
  • Ability to speak and understand Dutch or English without a translator
Not Eligible

You will not qualify if you...

  • Unwillingness to consent to the study or to audio recording
  • No diagnosis of congenital hemophilia A for hemophilia patient group

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote) for eligibility assessment

Diagnostic Evaluation

Duration - At enrollment

Participants complete semi-structured interviews and focus groups to share their experiences and expectations regarding home monitoring in hemophilia A and anticoagulation treatment.

1 visit (in-person or remote) for interviews and focus groups

Long-term Monitoring

Duration - Ongoing during study participation until completion

Participants who perform home monitoring of hemostasis are observed to identify themes related to home monitoring impact and unmet needs.

No additional visits required; observations based on participant home monitoring activities

Trial Site Locations

Total: 1 location

1

Radboudumc

Nijmegen, Gelderland, Netherlands, 6525GA

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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